What is Placental growth factor (PGF)?

Placental growth factor is a protein that in bodies is encoded by the PGF gene.

Placental growth factor (PGF) is a affiliate of the VEGF (vascular endothelial growth factor) sub-family – a key atom in angiogenesis and vasculogenesis, in accurate during embryogenesis. The capital antecedent of PGF during abundance is the placental trophoblast. PGF is aswell bidding in abounding added tissues, including the bearded trophoblast.

Placental growth factor (PGF) is a protein-coding gene and a affiliate of the vascular endothelial growth factor (VEGF) family. PGF is ultimately associated with angiogenesis. Specifically, PGF plays a role in trophoblast growth and differentiation. Trophoblast cells, accurately extravillous trophoblast cells, are amenable for advancing affectionate arteries. Able development of claret argosy in the placenta is acute for able beginning development. Under accustomed physiologic conditions, PGF is aswell bidding at a low akin in added organs including the heart, lung, thyroid, and ashen ashen muscle.


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