Cidofovir is a new anti-viral drug. It is classified as a nucleotide alternation and is alive adjoin canker cytomegalovirus (CMV) retinitis infection. Most adults are adulterated with CMV. Cidofovir suppresses cytomegalovirus (CMV) principaletype by careful inhibition of viral DNA synthesis.
Cidofovir acts through the careful inhibition of viral DNA polymerase.Biochemical extracts abutment careful inhibition of CMV DNA polymerase by cidofovir diphosphate, the alive intracellular metabolite of cidofovir. Cidofovir diphosphate inhibits herpesvirus polymerases at concentrations that are 8- to 600-fold lower than those bare to arrest animal cellular DNA polymerase alpha, beta, and gamma. Incorporation of cidofovir into the growing viral DNA alternation after-effects in reductions in the amount of viral DNA synthesis.