Application: An antiproliferative agent that inhibits topoisomerase II
CAS Number: 6377-18-0
Molecular Weight: 640.6
Molecular Formula: C32H32O14
Solubility: Soluble in water (partly miscible), and acetone.
Storage: Store at 4° C
Density: 1.6 g/cm3 (Predicted)
Chartreusin is a almighty anti-proliferative abettor originally acquired from Streptomyces chartreusis. This admixture has been apparent to be a almighty inhibitor of the catalytic action of Topo II (topoisomerase II). Experiments accept appear that Chartreusin binds to GC-rich tracts in DNA, inhibits RNA synthesis, and causes single-strand scission of DNA via accumulation of chargeless radicals. Additionally, this abettor has been apparent to arrest accumulation of several DNA-protein complexes.