Aphrodisiac potentials of the aqueous abstract of Fadogia agrestis axis in macho albino rats.
Asian J Andrology. 2005. Yakubu MT, Akanji MA, Oladiji AT. Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria.
To appraise the phytochemical capacity and the amative abeyant of the aqueous abstract of Fadogia agrestis axis in macho albino rats. The aqueous axis abstract of the bulb was buried for phytochemical constituents. Macho rats were orally dosed with 18 mg/kg, 50 mg/kg and 100 mg/kg physique weight, respectively, of the abstract at 24 h intervals and their animal behavior ambit and serum testosterone absorption were evaluated at canicule 1, 3 and 5. Phytochemical screening appear the attendance of alkaloids and saponins while anthraquinones and flavonoids are abominably present. All the doses resulted in cogent access in arise frequency, intromission abundance and decidedly abiding the articulate cessation (P 0.05) and bargain arise and intromission latency. There was aswell a cogent access in serum testosterone concentrations in all the groups in a address evocative of dose-dependence. The aqueous abstract of Fadogia agrestis axis added the claret testosterone concentrations and this may be the apparatus amenable for its amative furnishings and assorted adult behaviors. It may be acclimated to adapt broken animal functions in animals, abnormally those arising from hypotestosteronemia.