Estrone (E1, and aswell oestrone) is an estrogenic hormone buried by the ovary as able-bodied as adipose tissue with the actinic name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the actinic blueprint C18H22O2. Estrone is an odorless, solid apparent powder, white in blush with a melting point of 254.5 °C and a specific force of 1.23.Estrone is one of several accustomed estrogens, which aswell cover estriol and estradiol. Estrone is the atomic abounding of the three hormones; estradiol is present about consistently in the changeable changeable body, and estriol is abounding primarily during pregnancy.
Estrone is accepted to be a carcinogen for animal females as able-bodied as could could cause breast amore or pain, nausea, headache, hypertension, and leg cramps. In men, estrone has been accepted to could could cause anorexia, nausea, vomiting, and arrect dysfunction.Estrone is accordant to bloom and ache states because of its about-face to estrone sulfate, a abiding derivative. Estrone sulfate acts as a backlog that can be adapted as bare to the added alive estradiol. It is the absolute estrogen in postmenopausal women.